Cytomegalovirus (CMV) testing during pregnancy is vital for detecting potential infections early, helping to prevent serious complications and protect your baby’s health from the very start.
Cytomegalovirus (CMV) is a common viral infection that can have serious implications during pregnancy. It is a member of the herpesvirus family and is typically spread through bodily fluids, such as saliva, urine, or blood. While CMV is harmless to most healthy individuals, it can pose significant risks to an unborn baby if a woman is infected for the first time during pregnancy or experiences a reactivation of the virus. CMV can cross the placenta and infect the developing baby, potentially leading to congenital CMV infection. This condition is a leading cause of hearing loss, developmental delays, and other long-term disabilities in children.
Congenital CMV infection occurs in approximately 1 in 200 newborns in the UK, but not all affected babies will experience symptoms. Preventative measures, such as practising good hygiene—particularly handwashing after changing nappies or wiping children’s noses—are crucial for reducing the risk of CMV transmission during pregnancy. For those diagnosed with CMV, early detection through prenatal testing, such as amniocentesis, and close monitoring by a specialist can help manage the condition. Public health awareness about CMV and its potential impact on pregnancy is essential, as many women remain unaware of the virus and its risks.
Cytomegalovirus (CMV) testing during pregnancy is essential for identifying potential risks to the baby, as CMV is a common infection that can cause significant complications. According to NICE guidelines (August 2021), routine CMV testing is not universally recommended in antenatal care due to the lack of proven interventions to prevent transmission or manage congenital CMV effectively. Pregnant women should be informed about CMV prevention strategies, such as regular handwashing and avoiding contact with saliva from young children, as this group is a common source of transmission. Testing may be considered in specific high-risk cases, such as when symptoms suggest an active infection or if fetal anomalies are detected during an ultrasound.
In a more recent development, a landmark research paper highlights the importance of early diagnosis and monitoring when CMV infection is suspected during pregnancy. Targeted testing can help confirm maternal infection and assess fetal risk. Managing CMV focuses on counselling parents about potential outcomes and, in some cases, antiviral therapies to reduce viral load. For optimal outcomes, pregnant women should receive comprehensive guidance on CMV risks, preventive measures, and available diagnostic options to make informed decisions about their care. Early intervention can significantly improve the health of both mother and baby.
Cytomegalovirus (CMV) is a common virus that belongs to the herpes family. Most people get CMV at some point in their lives, but many won’t even know they have it because it often causes no symptoms. In healthy individuals, the immune system keeps the virus under control, and it usually remains dormant without causing problems.
However, CMV can be a concern for people with weakened immune systems, such as those undergoing cancer treatment, organ transplant recipients, or individuals with HIV. It’s also a major concern during pregnancy because it can pass from the mother to the baby, potentially causing health issues for the baby, such as developmental delays or hearing loss.
CMV spreads through close contact with bodily fluids like saliva, urine, blood, semen, and breast milk. This means it’s often passed between young children, through sexual contact, or from mother to baby during pregnancy or breastfeeding. Sharing utensils, kissing, or touching infected surfaces and not washing your hands can also spread CMV.
Preventing CMV involves practising good hygiene, such as washing hands regularly with soap and water, especially after changing nappies or handling children’s toys. Pregnant women should avoid sharing utensils or drinks with young children and minimise direct contact with their saliva to lower the risk of transmission.
In most healthy adults and children, CMV causes no noticeable symptoms. If symptoms do appear, they may resemble mild flu-like illnesses, such as fatigue, fever, sore throat, or swollen glands. In rare cases, it can cause more severe symptoms, particularly in individuals with weakened immune systems or pregnant women.
CMV is usually diagnosed with blood tests that detect the virus or antibodies your body has produced in response to it. Sometimes, urine or saliva tests may also be used to confirm the presence of the virus, especially in newborns suspected of having a CMV infection.
CMV is one of the most common infections that can pass from a pregnant mother to her baby through the placenta. This is called congenital CMV, and it can sometimes lead to serious health problems for the baby, such as hearing loss, vision problems, seizures, or developmental delays. Babies born with CMV may also have a low birth weight or show signs of illness at birth.
Pregnant women are more likely to get CMV if they have frequent contact with young children, who are often carriers of the virus. While not every baby exposed to CMV will develop health issues, understanding the risks and taking precautions can help reduce the likelihood of transmission during pregnancy.
There is no cure for CMV, but in most cases, treatment is not necessary because healthy people can manage the virus on their own. For those with weakened immune systems or severe symptoms, antiviral medications can help control the infection and reduce complications. Babies with congenital CMV may also benefit from antiviral treatments to minimise the long-term effects of the virus.
The outlook for people with CMV depends on their overall health and whether complications develop. Most healthy individuals recover fully without lasting effects. However, early diagnosis and management are crucial for high-risk groups, such as pregnant women and immunocompromised individuals, to prevent serious health issues.
Congenital CMV (cytomegalovirus) occurs when a baby is infected with CMV before birth. This happens when a pregnant mother passes the virus to her baby through the placenta. While many babies with congenital CMV show no symptoms at birth, some can experience serious health problems such as hearing loss, vision issues, developmental delays, or seizures. It is one of the leading causes of birth-related disabilities worldwide. Early detection can help manage the condition and reduce the risk of long-term complications.
Treatment for congenital CMV often involves antiviral medications, such as ganciclovir or valganciclovir. These medicines can reduce the severity of symptoms and help prevent further complications, especially if started within the first few weeks of life. Supportive care, including regular hearing and vision tests, as well as therapy for developmental delays, may also be part of the treatment plan. Early intervention is key to improving the long-term outlook for babies affected by congenital CMV.
Routine CMV testing during pregnancy is not currently recommended in the UK for all pregnant women. This is because most CMV infections are mild and cause no harm to the baby, and testing every pregnant woman could lead to unnecessary worry and interventions. Additionally, there is no guaranteed way to prevent transmission to the baby, even if the mother is known to have CMV during pregnancy. The decision to test is usually based on specific risks or symptoms, such as abnormal ultrasound findings or concerns about a mother’s exposure to CMV.
At London Pregnancy Clinic we focus on educating our patients about reducing the risk of CMV transmission during pregnancy, such as practising good hygiene and avoiding contact with saliva and urine from young children. If a CMV infection is suspected or diagnosed, additional monitoring like specialised ultrasounds and further tests may be recommended. Targeted testing allows doctors to provide the best care for both mother and baby without unnecessary interventions.