Skip to main content

A Comprehensive Guide to AMH Blood Test: Its Significance and Connection to IVF

Ever wondered how a simple blood test could offer a glimpse into your fertility? In this blog post, we’ll delve into one of the most crucial hormones affecting fertility—the Anti-Mullerian Hormone (AMH). If you’ve heard of this hormone and wondered what role it plays in fertility or IVF treatments, you’re in the right place.

What is the AMH Blood Test?

An AMH (Anti-Mullerian Hormone) blood test measures the levels of AMH in a woman’s blood. Produced by the cells of the ovarian follicles, AMH serves as a reliable marker of ovarian reserve, effectively indicating a woman’s fertility potential. This test aids clinicians and fertility specialists in predicting a woman’s response to fertility treatments, particularly in vitro fertilisation (IVF).

What is the Anti-Mullerian Hormone (AMH)?

The Anti-Mullerian Hormone, first discovered by Alfred Jost in the 1940s, plays a crucial role in the sexual development of foetuses. AMH was initially known for its role in male sexual development, but subsequent research has unearthed its pivotal part in female fertility. In women, the hormone is released by the antral follicles, the small sacs in the ovaries that hold the eggs.

Why is the AMH Blood Test Important?

As AMH levels correspond to the number of remaining eggs in the ovaries, the AMH blood test offers a reliable gauge of a woman’s ovarian reserve. However, it’s essential to understand that AMH levels do not directly correlate with the quality of eggs.

Low AMH levels might indicate a diminished ovarian reserve, which could be a concern for women attempting to conceive naturally or through IVF. In contrast, higher AMH levels may suggest conditions like Polycystic Ovary Syndrome (PCOS).

When is an AMH Blood Test Required?

The AMH test may be recommended in several circumstances:

  1. Evaluating Ovarian Reserve: AMH levels help assess the number of eggs remaining in the ovaries. The test may be suggested for women approaching their mid-30s, those with a family history of early menopause, or those who’ve previously undergone chemotherapy or pelvic surgery.
  2. Diagnosing PCOS: Elevated AMH levels may be indicative of PCOS, a common condition affecting a woman’s ovaries and ovulation.
  3. Determining IVF Success: Before starting IVF treatment, clinicians may order an AMH test to better predict how the ovaries will respond to the fertility drugs used to stimulate egg production.

Connection between AMH Levels and IVF

The AMH blood test holds significant value in the field of assisted reproductive technology, especially IVF. It helps clinicians devise personalised treatment strategies for their patients.

For women with low AMH levels, special considerations may be needed during the stimulation phase of IVF. These women often respond less to ovarian stimulation, leading to a smaller number of eggs retrieved, which can affect the success rate of IVF. Conversely, women with high AMH levels might be at risk for Ovarian Hyperstimulation Syndrome (OHSS), a condition that can occur when the ovaries are overly stimulated by fertility drugs.

When is the Best Time to Have an AMH Blood Test?

An AMH blood test can be performed at any time during a woman’s menstrual cycle, as AMH levels remain relatively constant throughout. However, many fertility clinics might suggest the test as a part of an initial fertility assessment or prior to beginning fertility treatments like IVF.

In Conclusion

The AMH blood test serves as a potent tool in assessing a woman’s ovarian reserve and planning personalised fertility treatments. Whether you’re attempting to conceive naturally, preparing for IVF, or just wish to know more about your fertility, an AMH test could offer invaluable insights. Always consult with a fertility specialist to discuss your options and understand what’s best for your individual circumstances.

Discover more about the Blood Tests we offer at London Pregnancy Clinic.

Pregnancy Testing – Deep Dive into the Beta HCG Test

Pregnancy tests aim to provide a simple yet effective method of determining if you’re pregnant. There are two primary types of pregnancy tests available: urine tests and blood tests. While urine tests are more commonly used due to their convenience and over-the-counter availability, blood tests, specifically the Beta HCG (Human Chorionic Gonadotropin) test, offer a more detailed insight into the pregnancy. Here’s an in-depth look at the Beta HCG pregnancy test, how it differs from urine tests, its accuracy, uses, and how to interpret the results.

What is a Beta HCG Pregnancy Test?

A Beta HCG test is a blood test used to detect pregnancy. Human Chorionic Gonadotropin (HCG) is a hormone produced by the placenta after implantation. The beta subunit of HCG can be detected in the blood serum of expectant mothers approximately 11 days after conception; HCG can be detected in the urine 12-14 days after conception.

There are two types of HCG tests:

  1. Qualitative HCG test: This test simply detects the presence of HCG in the blood. It gives a “yes” or “no” answer to the question, “Are you pregnant?” Doctors often order this test to confirm pregnancy.
  2. Quantitative HCG test (Beta HCG): This test measures the specific level of HCG in the blood. It can detect even very low levels of HCG, making it a highly accurate test.

How Does a Beta HCG Test Differ from Urine Tests?

While both urine pregnancy tests and Beta HCG tests aim to detect the presence of HCG, there are distinct differences:

  1. Method of Testing: Urine tests can be done at home, while Beta HCG tests require a blood sample taken in a healthcare setting.
  2. Sensitivity: Beta HCG tests are more sensitive than urine tests and can detect lower levels of HCG. This means they can confirm pregnancy earlier than urine tests — typically around 11 days after conception.
  3. Information Provided: While urine tests only provide a positive or negative result, a Beta HCG test can provide more information about the pregnancy, like the approximate age of the fetus, or if there are potential complications.

The Accuracy of Beta HCG Pregnancy Test

Beta HCG tests are highly accurate. Because they can measure the exact amount of HCG in the blood, they can detect pregnancy earlier than urine tests, and they can also confirm or rule out potential problems.

However, while the Beta HCG test can detect if you’re pregnant, a single test can’t always accurately predict a healthy pregnancy. Levels of HCG can vary greatly among individuals, and a single measurement isn’t always indicative of a problem or complication. Doctors often will test HCG levels more than once, looking at how the levels change over time.

Uses of Beta HCG Pregnancy Test

Aside from confirming pregnancy, a Beta HCG test can be used for the following:

  1. Monitoring Pregnancy: Doctors may use Beta HCG tests to monitor the health of a pregnancy, particularly in the early weeks. They may use serial measurements to see if HCG levels are rising as they should.
  2. Identifying Ectopic Pregnancy: Lower than usual levels of HCG or levels that do not increase as they should may suggest an ectopic pregnancy — where the fertilized egg implants outside the uterus.
  3. Screening for Down’s Syndrome: As part of the “double,” “triple,” or “quadruple” screen test, the Beta HCG test can help assess a baby’s risk of Down syndrome.

Interpreting Beta HCG Test Results

Interpreting Beta HCG test results isn’t always straightforward, as normal HCG levels can vary widely. Typically, in a healthy pregnancy, HCG levels double approximately every 48 hours in the first weeks following conception.

However, unusually high or low levels, or levels that don’t increase as they should, might indicate a problem, such as an ectopic pregnancy, a miscarriage, or a potential chromosomal abnormality. In such cases, your healthcare provider will likely order further tests to determine the cause of the abnormal HCG levels.

It’s important to remember that while the Beta HCG test is a crucial tool in pregnancy monitoring, it is just one aspect of a larger picture. It should be used in conjunction with other tests and examinations to ensure a comprehensive understanding of both maternal and fetal health.

In conclusion, the Beta HCG pregnancy test is a sensitive, accurate, and versatile tool in the early detection and monitoring of pregnancy. By understanding its uses and how to interpret the results, you can gain a more comprehensive view of your pregnancy journey.

Here are typical ranges for hCG levels during pregnancy:

  • 3 weeks: 5 – 50 mIU/mL
  • 4 weeks: 5 – 426 mIU/mL
  • 5 weeks: 18 – 7,340 mIU/mL
  • 6 weeks: 1,080 – 56,500 mIU/mL
  • 7 – 8 weeks: 7,650 – 229,000 mIU/mL
  • 9 – 12 weeks: 25,700 – 288,000 mIU/mL
  • 13 – 16 weeks: 13,300 – 254,000 mIU/mL
  • 17 – 24 weeks: 4,060 – 165,400 mIU/mL
  • 25 – 40 weeks: 3,640 – 117,000 mIU/mL

Looking to book a blood test with us? Please visit our Blood Tests page. If you already had your pregnancy confirmed, we recommend to book an early pregnancy scan to check for the baby’s wellbeing.

Your Fertility Scan Guide 

Endometrial Lining Scan 

Endometrial Lining Scan, also known as the ‘Baseline Scan’, is designed to assess the thickness of the womb as well as its general outline and structure. 

These scans are popular amongst patients going through IVF treatment and are designed to guide your referring clinician, helping them to understand and plan your treatment accordingly. This is done by estimating the best time and chances for conception in addition to preparation prior to embryo transfer. Book here.

London Pregnancy Clinic offer three price packages for Endometrial Lining Scans: 

  • Endometrial Lining Scan/Baseline Scan – £120 
  • One lining ultrasound scan 
  • Rose Package – £220 
  • Two lining ultrasound scans 
  • Lily Package – £320 
  • Three lining ultrasound scans 

Follicular Tracking Scan 

Follicular Tracking Scan, also known as Antral Follicle Count, assesses the total number and size of the follicles in each ovary. 

These scans are popular amongst those going through IVF treatment. Follicle Tracking Scan helps your referring clinician to make important decisions in your fertility treatment and as such it is imperative to get accurate readings. Book now.

Similar to Endometrial Lining Scan, we offer three price packages for Follicular Tracking Scans: 

  • Follicle Tracking Scan/Antral Follicle Count: £150 
  • One follicle tracking ultrasound scan 
  • Rose Package – £270 
  • Two follicle tracking ultrasound scans 
  • Lily Package – £390 
  • Three follicle tracking ultrasound scans 

HyCoSy Scan 

This is an advanced ultrasound scan to examine the fallopian tubes, uterus and ovaries providing an important insight into your fertility. 

HyCosy scans are performed by our expert Consultant Gynaecologist, Mr Prashant Purohit, specialises in reproductive medicine and fertility assessment. HyCoSy scans are recommended for patients who have experienced difficulties in getting pregnant. Book now.

  • Cost: £500 including a pre-procedure consultation 

Blood Test Services 

London Pregnancy Clinic offers a variety of different blood tests with a short turnaround time. The results will be sent to you and your referring consultant through our secure online system. 

  • 1
  • 2